ANTIBACTERIAL ACTIVITY TEST OF LAMTORO (LEUCAENA LEUCOCEPHALA L.) SEED INFUSION AGAINST PROPIONIBACTERIUM ACNES

Abstract

Background: Lamtoro, also known as Chinese petai, is a wild plantaa found throughout Indonesia, including Papua. Lamtoro plants are commonly used by people as traditional medicine to heal wounds, treat worms, and treat acne. The part used is the seeds of the lamtoro plant (Leucaena leucocephala L.), which contain alkaloids, flavonoids, saponins, and tannins, which have the potential as antibacterials. Objective: to determine the inhibitory activity of lamtoro seed infusion extract (Leucaena leucocephala L.) at concentrations of 12.5%, 25%, and 50% against Propionibacterium acnes. Method: This research is an experimental study conducted in May 2025 at the Integrated Laboratory of the Ministry of Health Polytechnic of Jayapura and the Basic Biology Laboratory of Cendrawasih University. Results: The three concentrations tested had inhibitory power against Propionibacterium acnes with an average diameter formed at a concentration of 12.5% ​​of 8.19 mm, a concentration of 25% of 9.60 mm, and a concentration of 50% of 9.76 mm. Conclusion: In this study, it can be concluded that the extract of lamtoro seed infusion with concentrations of 12.5%, 25% and 50% has moderate antibacterial activity against Propionibacterium acnes.